The history of creation of Viagra

history of creation

In fact, the history of creation of Viagra is quite curious. Literally, an amazing remedy for erectile dysfunction appeared accidentally. Initially, scientists tried to invent a medicine that will cure people with serious heart diseases. On the other hand, Viagra is not the first drug with an unexpected effectiveness. Maybe you remember that once approximately the same happened with antibiotics. Almost a century ago in Britain a mold was found, which quickly and easily destroyed different types of bacteria. Researchers studied the properties of that mold, and discovered penicillin. It changed the whole world, and is still successfully used in treatment.

sunstance sildenafilViagra was invented almost the same way. In the early nineties, in the UK pharmacologists were working on a new drug for the treatment of chronic heart diseases. They expected that the invention would help reduce blood pressure, and affect the blood flow in the myocardium. But when it came to testing the medicine in humans, the drug developers were surprised. Most of the men who participated in the clinical study noticed ... a delightful erection. According to legends, which now can hardly be confirmed or disproved, many participants of the study just didn’t give the unused medicine back to scientists. But can we blame them? They suddenly got an opportunity to enjoy a strong erection anytime. Previously, men had to visit a psychotherapist for years and years, or even had surgeries to improve their sex life. Viagra, originally invented as a heart drug, solved erection problems instantly.

Further studies of the drug, already as an impotence remedy, lasted for several years. The newly discovered properties of Viagra for improving male potency were carefully studied and confirmed from 1993 to 1998, when the medicine finally officially appeared on the market. You know what happened next. Since 1998 and until now, Viagra remains the best way to stay on top.

Discovery of the main active substance Sildenafil

Viagra is Sildenafil

How did it all start? The discovery of the main active substance Sildenafil was not accidental. But nobody expected such an effect. Initially, the developers of Viagra were trying to create a drug that affects blood flow and blood pressure. It was supposed that the active ingredient of Viagra would cure people with heart diseases, reducing blood pressure and improving myocardial blood flow. In 1992, these properties of Sildenafil were at the center of the studies conducted.

Directions of use of the substance

Researchers are still working on Viagra properties. Directions for the use of the substance Sildenafil, which is responsible for the magic of Viagra, are potentially numerous. If one detects something new in the mechanism of action of the active ingredient on relaxation of smooth muscles, the medication will only get better. Maybe Viagra will become even more effective in combating all kinds of impotence.

Effect on the heart muscle

The main task of scientists and pharmacists is to evaluate the possibility of Viagra's influence on the cardiac muscle. After all, the medicine was first created for this purpose. Who knew that Sildenafil would be more effective for muscles and blood vessels in the penis area? Nevertheless, the active substance of Viagra still has some influence on the cardiac muscle, and may even be used to treat pulmonary arterial hypertension. The reason is that Sildenafil is an inhibitor of phosphodiesterase 5. Due to this, it affects the smooth muscles, improving the flow of blood.effect on the heart muscle

What is the connection between the heart and erectile function?

Briefly, what is the connection between the heart and erectile function in men? First of all, the active ingredient Sildenafil is responsible for the blood flow. It was even assumed that its ability to improve bloodstream would positively affect the function of the heart. However, the blood flow is also very important for the male genitals. So, the penis should be grateful to Viagra for the improved blood flow in the pelvic zone. Of course, a strong erection itself can also affect the heart, but only if you have health problems. Normally, Sildenafil works exactly where it’s needed.

Availability and use of the drug at the dawn of creation

Today, Viagra is quite affordable. Even a student can buy a small package in the minimum dosage. Besides, young men usually need smaller amounts of Sildenafil to act great. But what was the availability of the drug at the dawn of its existence? How did the first patients use Viagra? According to a legend, one of the participants of the first clinical study of Sildenafil came back to the laboratory at night to steal himself a bit of Viagra. Well, he quickly realized exactly how it works!